GRAIL, Inc.

A Historic Moment in the Fight Against Cancer

Congress has taken a historic step forward in the fight against cancer. Thanks to the leadership of its bipartisan sponsors, and the work of advocates across the country, the Nancy Gardner Sewell Medicare Multi-Cancer Early Detection Screening Coverage Act is now law following the President’s…

Why Finding Cancers Before It’s Too Late Matters More Than Ever

The potential life-saving impact of reducing Stage IV disease and detecting more cancers at Stage III When people think about cancer screening, the emphasis is almost always on finding cancers as early as possible. That goal makes intuitive sense, but it can lead to an important oversight. The…

The NHS-Galleri trial: What to expect in 2026 from the world’s first randomized controlled trial of a Multi-Cancer Early Detection test, Galleri®

As the multi-cancer early detection (MCED) field evolves, we and others have asserted that it is essential – in order for individuals to have confidence in a test – that it must have demonstrated performance in a prospective trial in the intended use population ( Read more at GRAIL

PATHFINDER 2: What to Expect from the Largest U.S. Multi-Cancer Early Detection (MCED) Interventional Trial

Cancer screening has transformed outcomes for several cancers, but the vast majority of cancer deaths still occur in patients who have cancers without recommended screening tests. Multi-cancer early detection (MCED) tests can help address that gap. Rather than screening for one cancer at a time,…

Making Sense of the Numbers: Interpreting Multi-Cancer Early Detection Test Performance

View the white paper here. Read more at GRAIL

Not All MCED Tests are Created Equal: The Realities of MCED Test Development and Validation

By Joshua Ofman MD, MSHS, GRAIL President; Megan P. Hall Ph.D., GRAIL Medical Affairs; Christina Clarke Dur Ph.D. GRAIL Cancer Epidemiology Multi-cancer early detection (MCED) tests hold enormous promise, but will only achieve their public health and clinical impact if the tests are validated…