Nuclera

Antibody Discovery: Cell-Free Protein Synthesis vs CHO Guide

Antibody Discovery: Cell-Free Protein Synthesis vs CHO Guide   Mammalian expression is the gold standard in antibody discovery for detailed kinetic profiling, functional assays, developability, and manufacturing-relevant scale-up. However, early-stage antibody discovery workflows often begin with a…

Built for AI Antibody Design. Accelerating the DBTL Cycle.

AI antibody design generates candidates faster than wet labs can validate them, creating a bottleneck in the Design-Build-Test-Learn (DBTL) cycle. Teams can model massive in silico libraries, but lack a rapid workflow to generate the physical evidence to classify which sequences express, bind, or…

Overcoming the AI Antibody Validation Bottleneck with Early Hit Triage

The Missing Triage Step in AI Antibody Discovery Artificial intelligence has fundamentally rewired the front end of antibody discovery. Today, generative models and zero-shot de novo design platforms can computationally generate and rank thousands, or even millions, of target-specific sequences in…

Nuclera launches antibody triage service to advance AI-driven antibody discovery

Rapid binder triage, of AI-driven candidate sets, enables early elimination of non-binders ahead of costly downstream workflows Powered by cell-free technology to convert AI-generated candidates into experimental binding data Cambridge, UK and Boston MA, USA 11 May 2026: Nuclera, the biotechnology…

Nuclera launches GPCR-focused nanodisc panel to streamline membrane protein production

Enables expression of active GPCRs in 48 hours Panel supports screening to scale-up on eProtein Discovery Cambridge, UK, and Boston MA, USA, 30 March 2026: Nuclera, the biotechnology company enabling rapid access to high-quality proteins, today announced the launch of its nanodisc panel to support…

Webinar recap: Frank Bernhard’s Cell-Free Workflow for Cryo-EM–Ready Membrane Protein Complexes

Webinar recap: Frank Bernhard’s Cell-Free Workflow for Cryo-EM–Ready Membrane Protein Complexes When dealing with complex G protein-coupled receptors (GPCRs), traditional cell-based expression of membrane proteins often results in toxicity, aggregation, or the need for heavy engineering just to get…