Office Manager

The Office Manager is fully responsible for the day‑to‑day operations, efficiency, and overall workplace experience across all MBX office locations, including lab-related partnerships and needs. This role ensures a well‑functioning, organized, and engaging environment by proactively managing office functions, vendor relationships, space utilization, and onsite logistics. In addition to overseeing multi‑site operations, the Office Manager plays a key role in coordinating Together Weeks and other company‑wide initiatives that strengthen the employee experience and foster a connected MBX community. They also support the planning and execution of large meetings and events, enabling seamless collaboration.

The Office Manager owns all aspects of office operations and outcomes, acting as a strategic partner in shaping the workplace to support productivity, connection, and company culture. They are expected to anticipate needs, solve problems proactively, and continuously improve the workplace experience to meet evolving business and employee demands.

Own and manage all aspects of office operations, ensuring a seamless and high-quality workplace experience

Serve as the main point of contact for the company's “together weeks”.

Provide full-time, proactive oversight of daily office needs, functions, policies, and procedures

Serve as the central point of contact for all office-related coordination and inquiries

Serve as the primary liaison with the landlord and onsite building management, coordinating facility-related requests, maintenance activities, access needs, and issue resolutions

Manage vendor relationships (cleaning, maintenance, supplies), including contracts, renewals, and performance

Oversee facilities management, including repairs, maintenance planning, office improvements, and space optimization

Track and manage the office budget, approvals, and identify cost savings opportunities

Anticipate needs, maintain inventory levels, and oversee ordering and cost control

Plan and execute employee engagement initiatives, in-office events, onboarding, and culture-building activities

Coordinate new hire setup, including IT needs, workspace, equipment, access, and welcome experience

Manage workspace strategy, including seating arrangements, hybrid schedules, growth planning, and continuously improving processes, policies, and long-term solutions

Ensure the office reflects the company brand, values, and culture

Create a consistent and positive experience for visitors, candidates, and employees.

May present key office updates and metrics at respective company meetings as needed

Other responsibilities as assigned

5+ years of experience in office management, workplace operations, facilities, or a similar role

Proven ability to independently manage office operations with full ownership and accountability

Strong experience managing vendor relationships, contracts, negotiations, and performance

Demonstrated ability to manage budgets, track expenses, and identify cost-saving opportunities

Excellent organizational, project management, and multitasking skills with high attention to detail

Proactive, solutions-oriented mindset with the ability to anticipate needs and resolve issues before they arise

Strong interpersonal and communication skills with the ability to collaborate across all levels of the organization

Experience planning events, employee engagement initiatives, and onboarding programs

Familiarity with facilities management, space planning, and workplace strategy (including hybrid work environments)

Ability to create, implement, and enforce policies, procedures, and best practices

Comfortable working with office technology systems (e.g., ticketing systems, inventory tools, workplace apps, MS Office/Google Workspace)

Ability to analyze trends, identify gaps, and implement long-term operational improvements

High level of professionalism, discretion, and customer-service orientation

This position requires on-site work an average of four days a week. You will be expected to travel periodically based on the needs of the business to the extent requested by the Company, including attendance at Together Weeks, Together Days, and functional meetings as requested by the Company.

MBX Biosciences is a biopharmaceutical company focused on the discovery, development and commercialization of novel precision peptide therapies based on its proprietary PEP™ platform, for the treatment of endocrine and metabolic disorders. The Company is advancing a pipeline of novel candidates for endocrine and metabolic disorders with clinically validated targets, established endpoints for regulatory approval, significant unmet medical needs and large potential market opportunities. The Company’s pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism preparing for Phase 3 development; and an obesity portfolio that includes MBX 4291 in Phase 1 development and MBX 5765 in preclinical development, as well as additional discovery candidates. The Company is based in Carmel, Indiana and Burlington, Massachusetts. To learn more, please visit the Company website at www.mbxbio.com and follow it on LinkedIn.

MBX Biosciences is an Equal Opportunity Employer and is committed to treating all applicants fairly without discrimination. We welcome applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law.