Associate Scientist II, QTAS

The QTAS Department within AbbVie’s South San Francisco location is seeking a highly motivated scientist to support the creation and implementation of flow cytometry (FCM) based pharmacodynamic cell-based assays that promote the development of novel therapies from the bench to the clinic. In addition, the ideal candidate will have a strong background in pharmaceutical sciences, bioinformatics, ability to drive cutting-edge science and work in a matrix environment. The candidate will work in a highly collaborative environment with the overall objective to incorporate emerging technologies and streamline data analysis for early and late-stage drug development pipelines. In addition, you will have opportunities to contribute to broader areas within QTAS as your experience and expertise warrants.

Work as part of a highly collaborative interdisciplinary team in an integrated early drug development laboratory

Conduct laboratory studies in support of pharmacodynamic biomarker development and execution of individual immune-oncology and immunology R&D projects using flow cytometry

Independently design, implement and monitor flow cytometric biomarker assays as well as data collection in early pre-clinical and clinical trials

Minimum 1 year of hands-on experience in both conventional and spectral flow cytometry: BD Fortessa X20, BD Symphony, and Cytek Aurora/Aurora Evo

Maintaining existing R coding scripts in support of preclinical and clinical biomarker data

Implement bioinformatic scripts and develop data visualization approaches for preclinical studies

Evaluate emerging algorithms and approaches to improve rigorous assay development and internal quality control measures

Interact with cross-functional teams to establish productive collaborations

Bachelor’s Degree, or equivalent education, with typically 3 or more years’ experience or Master’s Degree or equivalent education (no additional experience)

Must have 1+ years of hands-on flow cytometry experience

Able to work with various BD instruments (i.e. Fortessa, Symphony) and Cytek Aurora

Experienced with various flow cytometric analysis software including OMIQ and FlowJo is essential

In depth knowledge of fluorochromes and familiarization with complex multi-color flow cytometry are highly desirable

Prior experience with R and Python coding languages and data visualization approaches are required

Strong and relevant publication record in the bioinformatics, immune-oncology, and immunology fields

Highly motivated, self-driven and results-oriented person with excellent communication and presentation skills,

Work both as a team player and independent scientific contributor

Passion for generating ideas, learning, solving technical problems and applying new technologies to further scientific goals

Basic knowledge in Immunology and of various immune cell populations is a plus

Able to handle multiple projects and highly attentive to details

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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