The QTAS Department within AbbVie’s South San Francisco location is seeking a highly motivated scientist to support the creation and implementation of flow cytometry (FCM) based pharmacodynamic cell-based assays that promote the development of novel therapies from the bench to the clinic. In addition, the ideal candidate will have a strong background in pharmaceutical sciences, bioinformatics, ability to drive cutting-edge science and work in a matrix environment. The candidate will work in a highly collaborative environment with the overall objective to incorporate emerging technologies and streamline data analysis for early and late-stage drug development pipelines. In addition, you will have opportunities to contribute to broader areas within QTAS as your experience and expertise warrants.
Work as part of a highly collaborative interdisciplinary team in an integrated early drug development laboratory
Conduct laboratory studies in support of pharmacodynamic biomarker development and execution of individual immune-oncology and immunology R&D projects using flow cytometry
Independently design, implement and monitor flow cytometric biomarker assays as well as data collection in early pre-clinical and clinical trials
Minimum 1 year of hands-on experience in both conventional and spectral flow cytometry: BD Fortessa X20, BD Symphony, and Cytek Aurora/Aurora Evo
Maintaining existing R coding scripts in support of preclinical and clinical biomarker data
Implement bioinformatic scripts and develop data visualization approaches for preclinical studies
Evaluate emerging algorithms and approaches to improve rigorous assay development and internal quality control measures
Interact with cross-functional teams to establish productive collaborations
Bachelor’s Degree, or equivalent education, with typically 3 or more years’ experience or Master’s Degree or equivalent education (no additional experience)
Must have 1+ years of hands-on flow cytometry experience
Able to work with various BD instruments (i.e. Fortessa, Symphony) and Cytek Aurora
Experienced with various flow cytometric analysis software including OMIQ and FlowJo is essential
In depth knowledge of fluorochromes and familiarization with complex multi-color flow cytometry are highly desirable
Prior experience with R and Python coding languages and data visualization approaches are required
Strong and relevant publication record in the bioinformatics, immune-oncology, and immunology fields
Highly motivated, self-driven and results-oriented person with excellent communication and presentation skills,
Work both as a team player and independent scientific contributor
Passion for generating ideas, learning, solving technical problems and applying new technologies to further scientific goals
Basic knowledge in Immunology and of various immune cell populations is a plus
Able to handle multiple projects and highly attentive to details
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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Originally posted by AbbVie Inc.. View original posting
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