Director, Alliance Management

Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.

Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.

This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.

The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts.

The Associate Director/Director, Alliance Management is responsible for leading and optimizing strategic collaborations with pharmaceutical, biotechnology, academic, and technology partners. This role serves as the primary relationship manager for one or more high-value alliances, ensuring alignment of strategic objectives, effective governance, operational excellence, and successful execution of contractual obligations.

The successful candidate will work cross-functionally with Research, Clinical Development, Regulatory Affairs, Commercial, Legal, Finance, Manufacturing, and Executive Leadership to maximize the value of partnerships while proactively identifying and mitigating risks.

The ideal candidate is a strategic, collaborative leader who excels at building trusted partnerships and navigating complex cross-functional environments and coordinating across internal and external stakeholders. They combine scientific understanding with business acumen, possess exceptional communication and influence skills, and have a demonstrated ability to maximize the value of strategic biotechnology alliances while ensuring operational excellence and long-term partner success. They drive alignment between internal priorities and partner expectations and ensure that Tango has a reputation as a good partner.

Strategic Alliance Leadership

Serve as the primary alliance manager for strategic research, development, licensing, and commercialization partnerships

Develop and execute alliance management strategies aligned with corporate objectives

Foster trusted relationships with partner organizations at operational and executive levels

Ensure partnerships achieve agreed milestones, deliverables, and value creation objectives

Governance & Collaboration

Establish and manage joint governance committees, including Joint Steering Committees (JSCs), Joint Development Committees (JDCs), and Joint Project Teams

Plan governance meetings, prepare agendas, facilitate discussions, document decisions, and track action items

Ensure effective communication and decision-making across partner organizations

Coordinate escalation and resolution of strategic or operational issues

Contract & Financial Management

Monitor compliance with collaboration agreements, licensing terms, and governance obligations

Coordinate milestone tracking and financial obligations, including payments, royalties, and budget planning

Partner with Legal on amendments, contract interpretation, and issue resolution

Support alliance-related forecasting and financial reporting

Monitor execution against project timelines and contractual commitments

Issue Resolution & Risk Management

Identify emerging partnership risks and develop mitigation strategies

Facilitate conflict resolution while maintaining productive long-term relationships

Escalate significant issues to executive leadership as appropriate

Performance Monitoring

Develop and monitor alliance performance metrics and KPIs

Conduct periodic health assessments of strategic partnerships

Recommend continuous improvement initiatives to enhance collaboration effectiveness

Excellent project management capabilities to manage respective alliances

Executive Communication

Prepare executive-level presentations, dashboards, and alliance status reports

Present partnership updates to senior leadership and governance committees

Support due diligence and integration planning for new collaborations

Advanced degree (PhD or MBA) with a minimum of 6 or 8 years of relevant alliance management experience, respectively, or a Bachelor’s degree with a minimum of 10 years of relevant alliance management experience

Demonstrated alliance management experience within the biotechnology or pharmaceutical industry

Global alliance management experience preferred

Experience managing complex research, clinical development, licensing, or commercialization collaborations

Knowledge of drug development from discovery through commercialization preferred

Preferred background in oncology or rare diseases

Experience with co-development, co-commercialization, or platform technology collaborations

Familiarity with alliance management best practices and tools

Hybrid OR On-Site OR US Remote eligible (with travel to headquarters in Boston, MA as required). #LI-Remote

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Salary range

$192,800—$298,200 USD