All jobs at Latch Bio

Infrastructure Engineer

Latch Bio

$180k – $250k/yrPosted Jul 31, 2026

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About LatchBio

We build the benchmarks that test whether frontier AI can actually do computational biology. Pharma, biotech, and solution providers rely on benchmarks.bio to evaluate and improve their AI systems - and we're just getting started.

We released the first rigorous benchmark suites for biology agents. They contain hundreds of real-world problems drawn directly from industry workflows. Our research shows that harness design - the tools, prompts, and control flow around a model - moves outcomes as much as swapping the base model itself. This insight is reshaping how frontier labs think about building with AI.

We've grown revenue 6x in the past 12 months. We have a repeatable sales process and deep partnerships with 10X Genomics, Vizgen, Takara Bio, and AtlasXOmics. More importantly: we have more demand than we can meet. That's why we're scaling rapidly across engineering.

We're building benchmarks across omics, therapeutics, and surveillance. We need engineers to build the infrastructure that powers our benchmarking pipeline - data ingestion, eval design, grading systems, and infrastructure. Work with scientists and frontier models. Ship fast.

Here is a sample of engineering products we work on

Agent harness integrated with bio first tooling such as an in-house h5ad and genomics viewer

Distributed file-system with metadata on Postgres and blobs on S3

Cluster orchestrator designed to accept compute nodes from anywhere on the internet

Reactive Python-based notebooks for data analysis and visualization

Benchmarking harness with automated QC processes to validate and probe model failure

cases

About this role

You will own the infrastructure layer of latch including container orchestration, distributed filesystems, cloud architecture, and database systems. While our team is operationally proficient, we do not have the bandwidth to tackle exciting areas of improvement such as speeding up container starts, improving filesystem throughput, scaling up RL operations, and reducing costs.

Signs of strong fit

Worked both on and with container orchestration systems such as K8s

Deeply proficient at postgres

Mastery of cloud primitives, especially AWS ones

Exceptional modern linux fundamentals like eBPF, cgroups2, etc

How we work

We care about output and let people optimize their work in a way that works for them. Our engineering team is in-person in San Francisco. We run a daily standup where engineers talk through technical challenges and stay aligned on what matters most. You will own a product area and execute, working closely with seasoned Latch engineers, product managers, and designers. Mentorship happens through code review and working through hard problems together.

Our charter and continued mission is to accelerate biological science so that humanity can benefit from better bioengineering, whether that be medical technology, farming, or environmental conservation. If you are motivated to work on these problems surrounded by like-minded people, LatchBio may be a great fit for you.

Who you'll work with

Engineering: Aidan, Ryan, Max, Anirudh, Joel, Tim

Product: Hannah, Nathan

Founders & Chief of Staff: Alfredo, Kyle, Kenny, Jordan

Hiring process

Our process is typically completed within two weeks.

Round 1: Introduction - Greg (Technical Recruiter)

Round 2: Live Coding Project (HackerRank)

Round 3: Technical - Latch Engineer

Round 4: Cultural - Aidan

Round 5: Final/ 1-Day Paid Onsite Project

Offer