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Senior Manager, PDS BI&T Architecture & Components

RayzeBio · New Brunswick, NJ

Posted Aug 2, 2026

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Working with Us Challenging. Meaningful.

Life-changing. Those aren’t words that are usually associated with a job.

But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department.

From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams.

Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Read more: <a href="https://careers.bms.com/working-with-us" target="_blank">careers.bms.com/working-with-us</a>.Senior individual-contributor role on the Architecture and Components team; works alongside a multidisciplinary group (UI, UX, AI Engineering, Full Stack, Architecture) within a globally distributed organization. This role does not manage people. Organizational Context As BMS Product Development & Supply (PDS) accelerates delivery of digital products and digital workers through Fusion Teams and scales adoption via Intelligence Hub, the organization requires clear ownership of architecture, reusable components, and technical decision-rights. The Analytics & AI Enablement (A&AIE) Architecture & Components Team is a highly technical team responsible for defining how digital solutions are built, ensuring they are scalable, operable, and future-ready through PDS Aim Points, with ambitions to revolutionize PDS use of AI by 2030–2035.

Rather than delivering individual use cases, this team establishes and stewards the shared architectural foundations and components — including those used for the foundational data pipelines, analytical models, and business-facing reports and dashboards — that enable broad, consistent execution across PDS. Position Summary This senior individual-contributor role will architect and build the shared, full-stack platform that powers analytics, digital products, and digital workers across PDS. The role focuses on distributed, multi-service systems that combine an orchestration layer, autonomous agents, shared services, and a federated frontend into a single internal platform-as-a-service — treated as reusable foundations rather than one-off use cases. You will work end to end, from async backend services and APIs through to modern web frontends, and you will design platforms that go beyond conversational interfaces to deliver autonomous analytical workflows, standardized tool-calling, and composable UI experiences.

This is a deeply hands-on, principal-level technical authority role; you set the bar through architecture, reference implementations, and engineering excellence. Key Responsibilities Platform & Multi-Service System Architecture <ul><li>Architect distributed, multi-service platforms that orchestrate work across autonomous services and agents, with conditional routing, parallel execution, and error recovery. </li></ul><ul><li>Design the platform as an internal SaaS/PaaS: shared SDKs, service contracts, and reusable components that solution teams consume rather than rebuild. </li></ul><ul><li>Build graph-based orchestration workflows combining LLM reasoning, business logic, real-time data integration, and enterprise security patterns. </li></ul><ul><li>Create reusable node/component libraries and extensible platform patterns supporting multiple business domains. </li></ul>Backend Development & API Design <ul><li>Build production FastAPI (or similar) applications with async I/O patterns for persistence and external services. </li></ul><ul><li>Implement Server-Sent Events (SSE) and WebSocket protocols for real-time streaming responses. </li></ul><ul><li>Design APIs and event-driven architectures for orchestration and service-to-service communication. </li></ul><ul><li>Develop robust error handling, graceful degradation, and enterprise security integration (SSO, access control), deploying containerized services via CI/CD. </li></ul>Frontend & Unified Experience <ul><li>Build modern web frontends (e.g., React) and design micro-frontend / Module Federation composition so independently built modules form one coherent experience. </li></ul><ul><li>Develop and steward a shared component library and design system used across the platform. </li></ul><ul><li>Design AI-enhanced UI patterns for streaming responses, chat, and analytical/canvas visualization. </li></ul>MCP Development & Dual-Intent Delivery <ul><li>Make MCP development and hosting a first-class platform capability, ensuring every solution is dual-intent: delivered both as a full-stack web experience and through Claude Desktop. </li></ul><ul><li>Design, build, and host production MCP servers that expose platform services and tools so the same underlying capabilities power both the web UI and Claude Desktop, with no divergence between the two surfaces. </li></ul><ul><li>Define golden-path patterns, templates, and shared MCP servers (tools, resources, prompts, transport, and authentication) that solution teams reuse to ship dual-intent solutions quickly. </li></ul><ul><li>Establish MCP hosting, versioning, security, and operational standards for seamless, enterprise-grade integration with Claude Desktop. </li></ul>LLM Integration, Orchestration & Tool Calling <ul><li>Integrate cloud LLM providers (AWS Bedrock or comparable) into platform services. </li></ul><ul><li>Design prompt management with versioning, templating, and dynamic compilation. </li></ul><ul><li>Implement conversation/state persistence (e.g., Redis checkpointing) for multi-turn workflows. </li></ul><ul><li>Build standardized tool-calling that connects agents and external clients to data sources and services, with the Model Context Protocol as the primary integration surface. </li></ul>Reusability, Observability & Optimization <ul><li>Treat internal developers as customers: provide golden-path templates, clear contracts, and documentation that accelerate delivery. </li></ul><ul><li>Define standards for versioning, contracts, and backward compatibility across the component ecosystem. </li></ul><ul><li>Integrate observability and tracing; build monitoring for performance, latency, cost, and quality, and optimize resource and token usage across production workflows. </li></ul>Cross-Functional Collaboration <ul><li>Partner with cloud, AI, data, and UX engineers on the team to integrate full-stack work with infrastructure, agentic capabilities, and interaction design. </li></ul><ul><li>Partner with Enterprise engineering and governance teams to align standards, controls, and shared services. </li></ul><ul><li>Provide technical mentorship on solution patterns, system design, and platform best practices, and contribute to architecture reviews and documentation. </li></ul>Desired Experience | Required <ul><li>Bachelor's or Master's degree in Computer Science, Engineering, AI, Data Science, or a related field. </li></ul><ul><li>6+ years of software engineering experience with deep full-stack delivery, including production experience building LLM-powered or agentic applications. </li></ul><ul><li>Strong Python, including async patterns (asyncio, async/await) and Python-based automation. </li></ul><ul><li>Production experience with async web frameworks (FastAPI or similar), REST, and event-driven / streaming architectures (WebSocket/SSE, queues, streams). </li></ul><ul><li>Strong working knowledge of modern web frontends (React) and micro-frontend / Module Federation composition; deep frontend and design-system expertise a strong plus. </li></ul><ul><li>Experience designing distributed, multi-service systems with well-defined contracts between components, and building an internal platform, SaaS/PaaS, or shared developer platform. </li></ul><ul><li>Experience with agentic orchestration frameworks (LangGraph preferred; LangChain, CrewAI, Autogen, or similar) and integration with cloud LLM providers (AWS Bedrock, Azure OpenAI, Anthropic, or OpenAI), including onboarding and standardizing these frameworks for solution teams. </li></ul><ul><li>Strong platform and cloud depth: Docker and Kubernetes / Amazon EKS, infrastructure-as-code (CloudFormation), Git and CI/CD, service mesh, policy-as-code (OPA/Gatekeeper), and production observability (e.g., Prometheus, Grafana, Loki) on AWS (Azure and/or GCP a plus). </li></ul><ul><li>Experience owning platform governance, security, and self-service onboarding for a shared platform — IAM/SSO, group-based authorization, and policy-as-code — acting as a technical gatekeeper for the teams that consume it. </li></ul>Critical Platform & Agentic Systems Experience <ul><li>Built autonomous, multi-step systems performing analytical tasks beyond simple chatbots. </li></ul><ul><li>Designed distributed platforms with service orchestration, conditional logic, and state management. </li></ul><ul><li>Developed and hosted production MCP servers with demonstrated adoption across capabilities. </li></ul><ul><li>Delivered dual-intent solutions where the same services power both a web experience and an LLM/desktop client via MCP. </li></ul><ul><li>Implemented standardized tool-calling for external system integration. </li></ul><ul><li>Designed shared SDKs/contracts and managed API/contract evolution across many consumers. </li></ul><ul><li>Prompt engineering at scale (templating, versioning, optimization) and understanding of agentic design patterns (ReAct, Plan-and-Execute, tool-use agents). </li></ul><ul><li>Strong problem-solving, communication, and ability to set technical direction and influence in globally distributed teams. </li></ul>Ideal Candidates Would Also Have <ul><li>Prior experience in global life sciences, pharma, or supply chain — especially in Product Development & Supply (PDS). </li></ul><ul><li>Experience in regulated environments (GxP, GDPR, PII) and embedding compliance into platform design. </li></ul><ul><li>Experience scaling an internal platform across multiple product/domain teams and managing the resulting contract and dependency surface. </li></ul><ul><li>Experience working internationally with globally dispersed teams. </li></ul>Other Qualifications <ul><li>Excellent communication skills and the ability to influence technical decisions without direct authority. </li></ul><ul><li>Hands-on experience implementing Agentic AI solutions and/or MCP is preferred. </li></ul><ul><li>Relevant cloud certification (e.g., AWS) is a plus. </li></ul>If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.<div><div><div><div><div><div><div><div><div><div><div><div><div><div>Compensation Overview:</div></div></div></div></div></div></div></div></div></div></div></div></div></div>New Brunswick - NJ - US: $134,980 - $163,564 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis.

Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience.

Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit <a href="https://careers.bms.com/life-at-bms/" target="_blank"> https://careers.bms.com/life-at-bms/.</a> Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment.

Our benefits include:<ul><li>Health Coverage: Medical, pharmacy, dental, and vision care.</li><li>Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).</li><li>Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.</li></ul>Work-life benefits include:Paid Time Off<ul><li>US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)</li><li>Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays</li></ul>Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers.

Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible.

Contractors, leased workers and other service providers are not eligible to participate in the program.Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has an occupancy structure that determines where an employee is required to conduct their work.

This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility.

Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture.

For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.Supporting People with DisabilitiesBMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer.

If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to <a href="mailto:adastaffingsupport@bms.com" target="_blank">adastaffingsupport@bms.com</a>. Visit <a href="https://careers.bms.com/eeo-accessibility" target="_blank">careers.bms.com/</a><a href="https://careers.bms.com/eeo-accessibility" target="_blank">eeo</a><a href="https://careers.bms.com/eeo-accessibility" target="_blank">-accessibility</a> to access our complete Equal Employment Opportunity statement.Candidate RightsBMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: <a href="https://careers.bms.com/california-residents/" target="_blank">https://careers.bms.com/california-residents/</a>Data ProtectionWe will never request payments, financial information, or social security numbers during our application or recruitment process.

Learn more about protecting yourself at <a href="http://careers.bms.com/fraud-protection" target="_blank">https://careers.bms.com/fraud-protection</a>.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at <a href="mailto:TAEnablement@bms.com" target="_blank">TAEnablement@bms.com</a>. Please provide the Job Title and Requisition number so we can review.

Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.R1604200 : Senior Manager, PDS BI&T Architecture & Components

Originally posted by RayzeBio. View original posting

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