Senior Research Associate, Preclinical
Terrestrial (formerly known as Vaxess) is developing a pipeline of next-generation vaccines and therapeutics on
our novel micro-array patch platform. With only five minutes of wear-time on the skin, the self-applied patch
enables up to two weeks of sustained delivery. The platform combines high temperature stability with simplified
application to dramatically alter the way that drugs are delivered. Terrestrial is committed to enabling products
that are not only more effective, but also more accessible to patients around the world.
The Role
We are seeking a talented, collaborative, and highly motivated individual to join our core team of preclinical
scientists and engineers contributing to the advancement of novel drug delivery modalities. This role is designed
for a versatile researcher who enjoys working at the translational interface of benchtop assay / model
development and in vivo validation. You will play a key role in characterizing the performance of our MAP
technology through a combination of mechanical testing, ex vivo skin assays, and preclinical study support. This is
a unique opportunity to be part of an emerging company bringing innovative microneedle therapeutic delivery
technology to the global market.
Responsibilities
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Ex Vivo & Benchtop Characterization of MAPs: Execute ex vivo skin deployment assays and support assay
development to evaluate MAP test article performance.
- ✓Mechanical Testing: Perform mechanical characterization of MAP test articles using instrumentation such as
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Instron force meters to ensure structural integrity and delivery efficiency.
In Vivo Study Support: Assist in the execution of PK and safety studies in rodent and swine models (as
needed), including animal model development and IND-enabling safety/efficacy studies.
Study Logistics: Coordinate tasks ranging from test article organization and vivarium logistics to tissue
harvest and downstream sample processing.
- ✓Data Analysis: Characterize MAP test articles deployed into various models via visual inspection, skin
penetration analysis, dose delivery metrics, and other biometric performance measurements.
- ✓Documentation: Maintain accurate laboratory records and electronic lab notebook (ELN) entries to support
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regulatory filings.
Collaboration: Contribute to study design, protocols, and report writing; communicate logistical needs and
present findings in cross-functional team meetings.
Travel: Travel to testing facilities in the greater Boston area as needed to transport test articles and support
studies.
Qualifications
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Education: Bachelor's or Master's degree in Bioengineering, Biomedical Engineering, Biology, Pharmacology,
or a related Life Science field.
Experience: Bachelor’s degree with 3+ years or Master’s degree plus 1+ years relevant work experience
required.
Technical Skills: Familiarity with basic wet lab techniques (e.g., micropipetting, buffer prep) is required.
Experience with mechanical testing (e.g., Instron), materials characterization, ex vivo tissue handling, or
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skin-based assays is highly preferred.
Preclinical Skills: Experience with animal models with or without pharmacokinetic endpoints is a plus.
Soft Skills: Strong organizational skills, attention to detail, and the ability to manage complex logistics in a
fast-paced environment.
Communication: Excellent verbal and written communication skills with a commitment to working
collaboratively within an interdisciplinary team.
Logistics: Ability to travel to and from local vivarium sites as required.
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The anticipated base salary range for this position is $76,000 - $96,000. Actual compensation will be determined
based on a variety of factors including experience, qualifications, and internal equity.
At Terrestrial, we’re bringing together exceptional talent to drive our product development forward. We value
collaboration, curiosity, and a dynamic work environment. To apply, please submit your CV/resume to
careers@terrestrialbio.com.
Terrestrial Bio, Inc, 11 Cummings Park Drive, Woburn, MA 01801 www.terrestrialbio.com