About this role
About the Job
Position Summary
A Principal Scientist at
BIB
is a highly motivated individual that works as the supervisor/project lead for one or more relevant projects, and mentors the involved junior scientists. Through significantly contributing to the operation of BIB and to strategically defining the direction of growth of BIB, the Principal Scientist at BIB is among the core members that significantly influence the performance and growth of BIB.
Responsibilities
Provide technical expertise and leadership in planning, designing, and conducting experiments, analyzing data and documenting results towards development and optimization downstream processes and/or achieving goals for cross functional development teams
Provide technical expertise and leadership in the technologically innovative efforts of the relevant project teams
Supervise setup, operation, and routine maintenance of AKTA, Process skid and equipment. Monitor processes to ensure consistency and reliability
Work independently, analyze and interpret experimental data, and present/document experimental results at meetings. Provide reports and prepare scientific presentations as needed. Write/revise batch records and technical reports
Play a lead role in strategically maintaining group awareness of relevant scientific literature and new technologies and business trends. Participate in/lead the evaluations of new technologies and their potential applications and business impacts. Maintain substantial knowledge of state-of-the art principles and theories and contribute knowledge base through literature review, conferences attendance and publication
Provide excellent judgements in the decision-making processes existing in the execution of a project
Provide technical coaching (matrix management) of and motivate junior staff members to high performance by providing mentoring, training, and appropriate supervision in process development activities
Manage resource planning and projects with excellent financial, timing, and priority awareness
Qualifications
Ph.D./MS/BS degrees in biochemistry, biomedical/biochemical engineering, or a closely related field
Ph.D. with ≥11 years or MS with ≥14 years or BS with ≥16 years of experience in downstream process development, scale-up and tech transfer to cGMP manufacturing facility in biotechnology.
SME in designing, developing/optimizing/characterizing chromatography, ultrafiltration/diafiltration, viral filtration/inactivation, and formulation for biologics drug substances development
Strong hands-on experience with AKTA purification systems (purifier, explorer, AKTA Pilot and Process skid) is required, ability for AKTA equipment trouble shooting is required.
SME with ion exchange, hydrophobic, mixed mode and affinity chromatography with AKTA purification systems, TFF process and filtration development
Excellent strategic views in judging business trends & their potential impacts, and proactive attitude to learn new technologies and manage changes in process development and process scale-up
Proven excellent management experience and leadership aptitude, and excellent financial awareness
Client focused, quality, results, productivity, and efficiency oriented, and science and innovation driven
Advanced written skills
Attention to detail, and the ability to multitask
Proficient with the use of MS Office software (MS Excel, MS Word, MS Powerpoint) and statistical DOE software including JMP, Minitab, Design Expert etc)
Flexible and results oriented