Research Associate II/Senior Research Associate

About this role

Thanks for visiting our Career Page. Please review our open positions and apply to the positions that match your qualifications.Research Associate II/Senior Research AssociateBothell, WAFull TimeProcess DevelopmentMid LevelShareSystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs).

SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development.

We offer an opportunity for you to learn and grow while making significant contributions to the company's success.TheResearch Associate II/Senior Research Associatewill assist in downstream protein purification, protein characterization, and process development. The position will directly report to a Downstream lead and assist in downstream process development and tech transfer to a GMP manufacturing facility. In this role, the individual will assist and operate both routine and advanced analytical instruments as well as protein purification systems.This position is full-time onsite at our new Bothell, WA location.

This role may occasionally need to work outside normal work hours.Key Responsibilities:Assist in downstream process development of molecules in pre-clinical and clinical pipelines. Process development activities include buffer preparation, chromatography method development and execution, TFF, and filtration operations and developmentAssist in performing routine purifications and analytical assays to support cell-line development, upstream, analytical, and formulation groupsExecute development experiments to produce scalable and robust purification processes via affinity chromatography, IEX, HIC and CHT, etc, using the ÄKTA FPLC platform. Execute development experiments to produce scalable and robust viral inactivation, viral filtration and tangential flow filtration processGenerate low endotoxin production runs for pre-clinical studiesPerform routine HPLC/UPLC, CE, cIEF, octet, ELISA and other biophysical techniques to support upstream, downstream, and formulation process developmentCompile, analyze, and report data for process development, tech transfer documentation, and other internal partnersAuthor standard operating procedures for biophysical assays and standard workflowsParticipate in timeline planningOther duties as assignedRequired Skills & Qualifications:MS or BS in Protein Science, Chemical Engineering, Biochemistry or a related field and relevant pharmaceutical or biotech experienceResearch Associate II- requires 2+ years of industry experienceSenior Research Associate- requires BS with 5+ years of experience or MS degree with 3+ years of industry experienceExperience with protein chromatography and filtration methods, and protein analysis techniquesAbility to execute SOPs and biophysical assays, and experiments designed for process development of pipeline molecules independentlyHands-on experience in:ÄKTA Protein Purification Systems and Unicorn softwareSEC-HPLC/UPLCPurification Process DevelopmentCrossflow and Tangential Flow Filtration techniquesColumn packing / unpackingViral inactivation and viral filtration process development / Viral clearance studyLow endotoxin production runProcess scale-down/scale-upCompensation and Benefits:The expected base salary range for this position is $70,000 - $90,000 annually.

Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.SystImmune is an Equal Opportunity Employer.

We welcome diverse talent and encourage all qualified applicants to apply.ShareApplyApply for this positionRequired*First Name*Last Name*Email Address*Phone*Address*Resume*We've received your resume. Clickhereto update it.Attach resumeorPaste resumeAttach resume as .pdf, .doc, .docx, .odt, .txt, or .rtf (limit 5MB) orPaste resumePaste your resume here orAttach resume fileAre you willing to relocate?No answerYesNoWhat's your citizenship / employment eligibility?*No answerI am a U.S. Citizen/Permanent ResidentNon-citizen allowed to work for any employerNon-citizen allowed to work for current employerNon-citizen seeking work authorizationI am a Canadian Citizen/Permanent ResidentOtherWhat's your highest level of education completed?*No answerGED or EquivalentHigh SchoolSome CollegeCollege - AssociatesCollege - Bachelor of ArtsCollege - Bachelor of Fine ArtsCollege - Bachelor of ScienceCollege - Master of ArtsCollege - Master of ScienceCollege - Master of Fine ArtsCollege - Master of Business AdministrationCollege - DoctorateMedical DoctorOtherCollege or University*Are you 18 years of age or older?*No answerYesNoLinkedIn Profile URL:*What languages do you speak fluently?Desired salary*Earliest start date?*Can you work weekends?*No answerYesNoCan you work evenings?*No answerYesNoCan you work overtime?*No answerYesNoIn 150 characters or fewer, tell us what makes you unique.

Try to be creative and say something that will catch our eye!150How many years of relevant pharmaceutical or biotechnology industry experience do you have?*Less than 2 years2–3 years3–5 years5+ yearsDo you have hands-on experience with downstream protein purification and purification process development using ÄKTA systems and UNICORN software?*YesNoDo you have hands-on experience with Tangential Flow Filtration (TFF), protein chromatography, and downstream process scale-up/scale-down?*YesNoConfirm you can work full-time onsite at our Bothell, WA office.*YesNoThe following questions are entirely optional.To comply with government Equal Employment Opportunity and/or Affirmative Action reporting regulations, we are requesting (but NOT requiring) that you enter this personal data. This information will not be used in connection with any employment decisions, and will be used solely as permitted by state and federal law. Your voluntary cooperation would be appreciated.Learn more.GenderDecline to answerFemaleMaleRace/EthnicityDecline to answerHispanic or LatinoWhite, not Hispanic or LatinoBlack or African-American, not Hispanic or LatinoAsian, not Hispanic or LatinoNative Hawaiian or Other Pacific Islander, not Hispanic or LatinoAmerican Indian or Alaskan Native, not Hispanic or LatinoTwo or More Races, not Hispanic or LatinoMENA (Middle Eastern and North African)Human Check*Submit Application