About this role
About Terrestrial Bio, Inc.
Terrestrial is transforming the delivery of next-generation therapies, starting with GLP-1.
Terrestrial's proprietary Tacterra™ microarray patch (MAP) and applicator platform consists of a patch resembling an adhesive bandage, which is applied with a preloaded applicator and removed after a few minutes. Once applied, each patch delivers bioactive tips into the skin, which dissolve quickly into the body, rapidly releasing their therapeutic payload. Designed for self-administration, the temperature-stable Tacterra™ platform enables precise, controlled delivery of a wide range of therapeutics without medical sharps or refrigeration.
Terrestrial has generated strong clinical and in-vivo proof of concept across multiple molecules. For more information, visit www.terrestrialbio.com.
Why this role
At Terrestrial Bio, IT is not a shared service. It is a strategic capability that will determine whether a highly regulated, fast-moving manufacturing operation can scale without losing control, compliance, or speed. We are building from scratch. We need a senior leader who can own that build — and then own the function it becomes.
Senior IT leaders rarely get to make every foundational decision. At this stage, you will define the architecture, choose the systems, build the team, and set the operating model — before scale locks those decisions in. You will report to the SVP of Operations with a clear and near-term path to the CFO, reflecting IT’s role as a core business function, not a support cost. This is a VP-track role for the right operator.
The Senior Director of IT will be Terrestrial Bio’s first internal IT executive: responsible for designing, building, and leading the technology infrastructure for a company scaling from 60 to 120+ people across three sites, consolidating into a new headquarters within 18 months — and growing well beyond that.
This is not a maintenance role. This is a build role with an executive mandate.
What you'll do
You will establish the IT function from the ground up and carry it through the company’s next phase of growth. That means:
Setting IT strategy and architecture in a greenfield, regulated manufacturing environment
Building and leading the internal IT team — hiring, developing, and retaining talent as the company scales
Owning the full technology stack: infrastructure, cloud, ERP, SaaS, networking, and security
Executing a complex site transition — one location to three, then consolidating into a new HQ
Establishing GxP-compliant IT governance, data integrity frameworks, and audit-readiness
Serving as the executive IT partner to Manufacturing, Quality, Finance, and Operations
Managing IT budget, vendors, and contracts with appropriate rigor for a regulated environment
Who you are
10+ years in IT, with at least 5 in a senior leadership role
Demonstrated experience building or standing up an IT function, ideally as first-in-seat
Deep expertise in infrastructure, cloud architecture, ERP, and enterprise security
GxP, 21 CFR Part 11, or equivalent regulated-industry IT compliance experience
Experience managing multi-site environments and major infrastructure transitions
Has built and led an IT function, not just managed one
Brings both startup scrappiness and enterprise discipline — and knows when to apply each
Understands GxP, data integrity, and the compliance expectations of regulated manufacturing
Can move fluently between infrastructure detail and board-level operational thinking
Has hired and developed IT teams in high-growth environments
Is trusted by engineers, operators, quality leaders, and executives alike
Preferred
Biotech, pharma, or medical device background strongly preferred
Experience supporting combination-product or device manufacturing a plus
B.S. in Computer Science, Information Systems, Engineering, or related field
Your impact
Within 12–18 months
IT infrastructure deployed, stable, and trusted across all sites
HQ transition executed without operational disruption
IT team in place and performing
GxP-compliant governance and audit-readiness established
IT operating as a strategic partner — not a reactive support function
Architecture and systems capable of supporting the next stage of company scale
Compensation: The anticipated base salary range for this position is $197,000 - $243,000. Actual compensation will be determined based on a variety of factors including experience, qualifications, and internal equity.
Onsite expectations: The majority of our roles at Terrestrial are either onsite or hybrid, which allows us to meet both business and team needs. Candidates applying must be willing to be onsite 4-5 days per week.
Location: Woburn, MA and our new, custom facility in Allston MA planned for Q4 of 2026.
At Terrestrial, we’re bringing together exceptional talent to drive our product development forward. We value collaboration, curiosity, and a dynamic work environment. We aim to recruit, employ, train, compensate and promote regardless of race, religion, color, national origin, sex, gender identity or expression, sexual orientation, disability, age, or veteran status.