About this role
About Terrestrial Bio, Inc.
Terrestrial is transforming the delivery of next-generation therapies, starting with GLP-1.
Terrestrial's proprietary Tacterra™ microarray patch (MAP) and applicator platform consists of a patch resembling an adhesive bandage, which is applied with a preloaded applicator and removed after a few minutes. Once applied, each patch delivers bioactive tips into the skin, which dissolve quickly into the body, rapidly releasing their therapeutic payload. Designed for self-administration, the temperature-stable Tacterra™ platform enables precise, controlled delivery of a wide range of therapeutics without medical sharps or refrigeration.
Terrestrial has generated strong clinical and in-vivo proof of concept across multiple molecules. For more information, visit www.terrestrialbio.com.
Why this role
We are seeking a talented, collaborative, and highly motivated individual to join our core team of preclinical scientists and engineers contributing to the advancement of novel drug delivery modalities. This role is designed for a versatile researcher who enjoys working at the translational interface of benchtop assay / model development and in vivo validation.
You will play a key role in characterizing the performance of our MAP technology through a combination of mechanical testing, ex vivo skin assays, and preclinical study support. This is a unique opportunity to be part of an emerging company bringing innovative microneedle therapeutic delivery technology to the global market.
What you'll do
Execute ex vivo skin deployment assays and support assay development to evaluate MAP test article performance
Perform mechanical characterization of MAP test articles using instrumentation such as Instron force meters to ensure structural integrity and delivery efficiency
Assist in the execution of PK and safety studies in rodent and swine models (as needed), including animal model development and IND-enabling safety/efficacy studies
Coordinate tasks ranging from test article organization and vivarium logistics to tissue harvest and downstream sample processing
Characterize MAP test articles deployed into various models via visual inspection, skin penetration analysis, dose delivery metrics, and other biometric performance measurements
Maintain accurate laboratory records and electronic lab notebook (ELN) entries to support regulatory filings
Contribute to study design, protocols, and report writing; communicate logistical needs and present findings in cross-functional team meetings
Travel to testing facilities in the greater Boston area as needed to transport test articles and support studies
Who you are
Minimum of BS and 5+ / MS and 4+ years relevant work experience or equivalent combination of work experience required
BS or MS in Bioengineering, Biomedical Engineering, Biology, Pharmacology, or a related Life Science field preferred
Familiarity with basic wet lab techniques (e.g., micropipetting, buffer prep) is required
Experience with mechanical testing (e.g., Instron), materials characterization, ex vivo tissue handling, or skin-based assays is highly preferred
Experience with animal models with or without pharmacokinetic endpoints is a plus
Strong organizational skills, attention to detail, and the ability to manage complex logistics in a fast-paced environment
Excellent verbal and written communication skills with a commitment to working collaboratively within an interdisciplinary team
Ability to travel to and from local vivarium sites as required
Compensation: The anticipated base salary range for this position is $76,000 - $96,000. Actual compensation will be determined based on a variety of factors including experience, qualifications, and internal equity.
Onsite expectations: The majority of our roles at Terrestrial are either onsite or hybrid, which allows us to meet both business and team needs. Candidates applying must be willing to be onsite 4-5 days per week.
Location: Woburn, MA until relocation to a new, custom facility in Allston MA planned for Q4 of 2026.
At Terrestrial, we’re bringing together exceptional talent to drive our product development forward. We value collaboration, curiosity, and a dynamic work environment. We aim to recruit, employ, train, compensate and promote regardless of race, religion, color, national origin, sex, gender identity or expression, sexual orientation, disability, age, or veteran status.