Research Fellow, Medicinal Chemistry

Vertex Pharmaceuticals Incorporated Oxford, UK Posted Sep 14, 2026
Location
Oxford, UK
Workplace
On-site / per employer
Posted
Sep 14, 2026

About this role

Job Description General Summary: We are seeking an outstanding medicinal chemist to join our team as a Chemistry Research Fellow (Director level). The ideal candidate has an impressive history of accomplishments which have contributed significantly to the advancement of projects and is recognized as a thought leader and an acknowledged expert in medicinal chemistry. Responsibilities will include leading the design efforts of small molecule targets across a project and driving best design practice across our portfolio of projects, including application of cutting-edge AI methodologies to key medicinal chemistry challenges.

Key Requirements and Responsibilities: Demonstrates intellectual and/or technological chemistry leadership Leads our science around molecular design, combining sound judgment, strong initiative and thorough methodology Helps to teach and develop employees throughout the group in the field of medicinal chemistry. Has a deep and thorough understanding of the small molecule drug discovery process. Drives the highest standards of data integrity and provides interpretations and recommendations to Project Teams Coordinates publication and patent submissions Will drive best practice in AI methodologies applied to small molecule drug discovery Education and Experience: Ph.D. (or equivalent degree) in chemistry or related science and relevant post-doctoral employment experience, or Masters Degree (or equivalent degree) in chemistry or related science and relevant employment experience, or Bachelors Degree (or equivalent degree) in chemistry or related science and relevant employment experience At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends.

We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Originally posted by Vertex Pharmaceuticals Incorporated. View original posting