About this role
We’re hiring a Principal Scientist in Cell Culture Development to join our team in Melbourne and play a key role in advancing biologics development. This is a senior technical role where you’ll lead upstream process development, provide scientific direction, and help bring high-quality recombinant products from early development through to manufacturing readiness. You’ll work across platforms, collaborate cross-functionally, and contribute to impactful programs that support patient outcomes.
Your Responsibilities: Provide scientific leadership and technical expertise in cell culture process development, optimisation, and scale-up Design and execute upstream development strategies across high-throughput and mid-scale platforms Lead and contribute to experimental planning, execution, and data interpretation with strong scientific rigour Suppor t process development across the full lifecycle from clone selection through to process characterisation Guide and mentor team members, sharing expertise and building capability Contribute to regulatory documentation and submissions Collaborate with cross-functional teams to enable tech transfer and manufacturing readiness Skills & Experience: Postgraduate degree (MSc, PhD, MEng or equivalent) in a relevant field Significant experience in cell culture process development (industry or advanced academic setting) Proven track record working with recombinant protein production or similar systems Comfortable working in cross-functional and multicultural teams Experience with the following is highly regarded: Mammalian cell culture, particularly CHO systems Early- and late-stage process development Media development and metabolic modelling Process optimisation aligned to product quality attributes Bioreactor scale-up and scale-down Technology transfer or implementation of manufacturing processes Why join us? Work on cutting-edge biologics development Influence key scientific and technical decisions Collaborate with a highly skilled, multidisciplinary team Be part of work that ultimately supports patient impact If you’re a scientist who enjoys combining deep technical expertise with leadership and collaboration, we’d love to hear from you. Applications Close on September 30, 2026 About CSL Behring CSL Behring is a global biotherapeutics leader driven by our promise to save lives.
Focused on serving patients’ needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives. CSL Behring operates one of the world’s largest plasma collection networks, CSL Plasma.
Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries. To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor visit https://www.csl.com/ and CSL Plasma at https://www.cslplasma.com/ . Our Benefits For more information on CSL benefits visit How CSL Supports Your Well-being | CSL .
You Belong at CSL At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future.
To learn more about inclusion and belonging visit https://www.csl.com/careers/inclusion-and-belonging Equal Opportunity Employer CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit https://www.csl.com/accessibility-statement .