About this role
Terrestrial Bio
Location: Allston, MA and Woburn, MA
About Terrestrial Bio, Inc.
Terrestrial is transforming the delivery of next-generation therapies, starting with GLP-1.
Terrestrial's proprietary Tacterra™ microarray patch (MAP) and applicator platform consists of a patch resembling an adhesive bandage, which is applied with a preloaded applicator and removed after a few minutes. Once applied, each patch delivers bioactive tips into the skin, which dissolve quickly into the body, rapidly releasing their therapeutic payload. Designed for self-administration, the temperature-stable Tacterra™ platform enables precise, controlled delivery of a wide range of therapeutics without medical sharps or refrigeration.
Terrestrial has generated strong clinical and in-vivo proof of concept across multiple molecules. For more information, visit www.terrestrialbio.com.
Why this role
Making microarray patches with hundreds or thousands of drug-loaded polymer microneedles — and ensuring consistent quality across a patch, a batch, or a manufacturing campaign — requires many processes to go just right, many, many times. This is where you get to dig in and make that happen. To that end, you will use your technical expertise to:
Get your hands on equipment and operations, building a first-principles understanding of how each unit operation affects product quality
Analyze process data to identify trends, troubleshoot deviations, and propose improvements
Grow your technical expertise by partnering with automation engineering, technical operations, and analytical/formulation development on real, moving problems, not hypotheticals
What you'll do
You will leverage your creativity, hands-on technical skills, and process engineering fundamentals to:
Characterize and improve manufacturing process unit operations by designing, executing, and analyzing process development experiments; communicate results via written reports and oral presentations to internal and project teams
Support manufacturing scale-up through hands-on assessment of novel equipment, workflows, analytical techniques/PAT, and process configurations
Support phase-appropriate cGMP manufacturing operations by drafting, revising, and reviewing process development histories, master batch records, process and equipment O&M SOPs, and other manufacturing documentation within Terrestrial’s Quality Management System
Develop and implement new or improved processes and controls to increase quality and throughput
Design tools, fixtures, and machines for manufacturing Terrestrial’s products
Collaborate closely with cross-functional teams to support product development and manufacturing activities
How you'll impact
Within your first 6–12 months, success likely looks like
Fluency with Terrestrial’s microarray patch manufacturing process and the unit operations behind it
Ownership of at least one process development experiment or equipment assessment, from design through results
Contributions to cGMP documentation — SOPs, batch records, or process development histories — that hold up to quality review
Trusted, hands-on partnership with automation, technical operations, and quality colleagues
Who you are
B.S. in Mechanical Engineering, Biomedical Engineering, Manufacturing Engineering, or a related discipline with 0-2 years of experience (internship, co-op, or academic research experience) for Process Engineer I and 3+ years of relevant hands-on experience in medical devices or pharmaceutical development/manufacturing for Process Engineer II
Experience with automated manufacturing equipment or process development strongly preferred
Hands-on experience designing, executing, and analyzing process development experiments, with strong data analysis and communication skills
Familiarity or experience working in a cleanroom and/or a biomedical laboratory environment
Comfort standing or sitting for up to 8 hours, and performing tasks on laboratory benchtops and within glovebox isolators
Relevant direct experience in medical devices or pharmaceuticals — internship, co-op, or prior work experience all count
Excellent time and project management skills, with a proven ability to meet goals and deadlines
Demonstrated ability to learn new skills and fields quickly, think independently, and collaborate across diverse, multidisciplinary teams
Come join our team to build enabling technologies for the future of intradermal delivery of therapeutics!
Compensation: The anticipated base salary range for the Engineer I - Engineer II position is $60,000 - $90,000. Actual compensation will be determined based on a variety of factors including experience, qualifications, and internal equity.
Onsite expectations: The majority of our roles at Terrestrial are either onsite or hybrid, which allows us to meet both business and team needs. Candidates applying must be willing to be onsite 5 days per week.
Location: Woburn, MA until relocation to a new, custom facility in Allston MA planned for Q4 of 2026.
At Terrestrial, we’re bringing together exceptional talent to drive our product development forward. We value collaboration, curiosity, and a dynamic work environment. We aim to recruit, employ, train, compensate and promote regardless of race, religion, color, national origin, sex, gender identity or expression, sexual orientation, disability, age, or veteran status.