About this role
苏州，中国 | 全职 | Job ID: 11911 About the role: As Associate Director, you will lead linker–payload chemistry and novel payload discovery for antibody–drug conjugates, helping advance differentiated therapeutic candidates. Your work supports BioNTech's mission to develop new treatment approaches for cancer.Based in Suzhou, you will build chemistry and bioconjugation capabilities and lead a specialist team. Working with colleagues across discovery, biology, drug metabolism, safety and process development, you will help guide programs from early research toward preclinical candidate selection.
Your contribution: Set the chemistry strategy for antibody–drug conjugate programs, aligning linker–payload platforms and emerging mechanisms with target biology and portfolio needs Design, synthesize and optimize linker–payload systems for potency, solubility, stability, controlled release and conjugation compatibility Establish bioconjugation, purification and analytical workflows with clear quality criteria for conjugates Evaluate new payload classes and mechanisms, and integrate chemistry, efficacy, drug metabolism and safety data to guide optimization and candidate selection Build and lead a chemistry and conjugation team, while planning resources and developing team membersDirect external collaborations and support robust documentation, intellectual property generation, safe handling and technology transfer A good match: PhD in organic chemistry, medicinal chemistry, chemical biology, pharmaceutical sciences or a related fieldBiopharmaceutical industry experience in antibody–drug conjugate linker–payload chemistry, medicinal chemistry and bioconjugation, including hands-on and supervisory work Track record designing and optimizing linker–payload systems and advancing antibody–drug conjugate programs; experience with novel payload classes is an advantage Strong knowledge of synthetic and medicinal chemistry, linker design, payload derivatization, structure–activity relationships and conjugation-compatible molecular design Proficiency in interpreting nuclear magnetic resonance, liquid chromatography–mass spectrometry, high-performance liquid chromatography and conjugate analytics Fluent English, with the ability to write and present technical information, negotiate technical matters and collaborate across borders; team leadership experience is preferred BioNTech 重视每一位团队成员的福祉，为多元化的员工提供全面的福利保障。我们提供具有市场竞争力的薪酬方案，具体将根据职位、工作地点及候选人资历与经验综合确定。注：各项福利的实际适用范围、享有条件及具体内容可能因所在地而异，最终以公司内部政策及当地法律法规为准。 申请方式： 请通过我们的在线申请链接提交以下材料： 个人简历 学位证书及职业资格证书复印件 联系方式 重要提示： 我们仅接受通过链接在线提交的求职申请。 提交申请即视为您知悉，招聘流程中将依相关法律法规进行背景调查。如您进入候选名单，BioNTech 将通过合作服务机构“HireRight”开展背景调查工作，招聘专员将及时与您沟通具体安排。 我们诚挚期待您的加入。