Synthetic DNA Process Development Scientist

Eurofins · Louisville, KY

Posted May 5, 2026

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products. In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

Position Summary

We are seeking a highly skilled and motivated Organic Chemist with expertise in oligonucleotide synthesis and purification to support process development and manufacturing. This role focuses on developing, optimizing, and scaling chemical processes for high-throughput and high-quality oligonucleotide production.

Key Responsibilities

Design, develop, and optimize chemical synthesis processes for nucleotides and oligonucleotides

Process development and scale-up from R&D to manufacturing

Develop and improve oligonucleotide purification processes (e.g., HPLC, ion-exchange, desalting)

Troubleshoot synthesis and purification challenges to improve yield and purity

Collaborate with manufacturing, QC, and engineering for process transfer

Evaluate new chemistries and technologies

Author SOPs, batch records, and technical reports

Ensure compliance with quality systems

Mentor lab technicians

Ph.D. or Master’s degree in Organic Chemistry or related field (required)

Minimum 5 years of industrial experience in chemical synthesis

Experience with solid-phase oligonucleotide synthesis

Experience in oligonucleotide purification process development

Strong analytical skills (HPLC, LC-MS)

Experience scaling processes to manufacturing

Preferred Qualifications

Experience in GMP or regulated environments

Familiarity with automated DNA/RNA synthesizers

Knowledge of modified nucleotides

Experience in high-throughput oligo production

Work Environment

Fast-paced, collaborative environment

Ability to manage multiple priorities

Occasional off-hours support as needed

Work Schedule

Location: Louisville, KY

Schedule: Monday–Friday, 8:00 AM – 5:00 PM

Weekend Work as needed

All your information will be kept confidential according to EEO guidelines.

Originally posted by Eurofins. View original posting

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