Senior Project Manager

Thanks for visiting our Career Page. Please review our open positions and apply to the positions that match your qualifications.Senior Project ManagerRedmond, WAFull TimeImmuno-OncologyMid LevelShareSystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ.

It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications.

Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development.

We offer an opportunity for you to learn and grow while making significant contributions to the company's success.We are seeking a Senior Project Manager, R&D to support cross-functional planning and execution for oncology biologics programs from early discovery through IND-enabling activities and support of IND submission. This role will partner closely with Research, Translational Sciences, Nonclinical, Regulatory, Clinical Pharmacology, and external partners to drive integrated development strategy, stage-appropriate planning, risk management, and operational execution.The ideal candidate brings strong biotech or biopharma drug development experience, excellent cross-functional leadership skills, and a deep understanding of the milestones, dependencies, and decision points required to advance innovative biologics programs into the clinic.

This individual will serve as a strategic and operational hub for assigned programs, ensuring alignment, accountability, and timely progress across the portfolio. A key aspect of this role is the effective use of meeting management to strengthen stakeholder integration, communication, decision-making, and execution across internal and external teams.Key ResponsibilitiesLead cross-functional project planning and execution for oncology biologics programs spanning target/lead discovery, candidate selection, IND-enabling studies, CMC development, and IND submissionBuild, maintain, and drive integrated project plans, timelines, milestones, scenarios, and critical path analyses across multiple functional areasPartner with program leaders and functional heads to define development strategy, key objectives, deliverables, governance milestones, and resource assumptionsFacilitate cross-functional team meetings, sub-team meetings, and governance reviews; document decisions, action items, risks, and next stepsIdentify interdependencies, operational risks, and potential bottlenecks early; drive mitigation plans and escalate issues appropriatelyEnsure alignment across Research, Nonclinical, CMC, Regulatory, Clinical, Biomarker/Translational, Quality, and partner organizationsDrive program team preparedness for major stage gates, including candidate nomination, development candidate selection, IND-enabling study initiation, and IND submissionSupport budget planning, resource tracking, and external partner/CRO coordination as neededDevelop concise and decision-oriented communications for senior leadership, governance bodies, and key stakeholdersTrack progress against program goals and proactively highlight deviations, tradeoffs, and decision needsPromote disciplined program management practices, clear accountability, and efficient team operationsContribute to portfolio planning and cross-program prioritization discussions where appropriateHelp apply and improve R&D project management tools, templates, dashboards, and best practicesDrive scalable adoption of AI-enabled and digital program management practices, including automation, dashboards, AI-assisted synthesis, standardized workflows, and data-driven reporting, to improve planning, meeting effectiveness, action tracking, knowledge management, risk identification, portfolio governance, and cross-functional execution while ensuring human oversight, data integrity, and compliance.Required QualificationsBachelor’s degree in life sciences, biomedical sciences, chemistry, engineering, or related field8+ years of relevant experience in biotech, biopharma, or related life sciences industry5+ years of project or program management experience supporting drug discovery and/or development programsDemonstrated experience managing biologics programs in oncology or closely related therapeutic areasStrong understanding of drug development from discovery through IND, including:discovery research and candidate selectionIND-enabling toxicology and pharmacologyCMC and analytical development for biologicsregulatory documentation and IND submission processesProven ability to lead highly matrixed, cross-functional teams without direct authorityExcellent communication, facilitation, organizational, and stakeholder management skillsStrong problem-solving abilities with demonstrated experience managing complex timelines, dependencies, and risksExperience preparing executive-level presentations, status reports, and governance materialsPreferred QualificationsAdvanced degree (MS, PhD, PharmD, or MBA) in a relevant scientific or business disciplineExperience with monoclonal antibodies, bispecifics, ADCs, or other complex biologic modalities in oncologyMandarin-English Bilingual AbilityPMP or related project management certification is a plus and biotherapeutics life cyclesExperience in a fast-paced, innovation-driven biotech environmentCore CompetenciesStrategic thinking with strong operational executionCross-functional leadership and influenceDecision facilitation and issue resolutionPlanning discipline and attention to detailAgility in a dynamic R&D environmentStrong sense of ownership and accountabilitySuccess in this role will be defined by the ability to:keep complex oncology biologics programs aligned and moving forward from discovery to INDcreate clarity across scientific and development teams around priorities, timelines, and decisionsanticipate risks and dependencies before they become delaysenable efficient governance and high-quality decision-makingbuild trust across functions as a strategic and operational partnerPosition Type/Expected Hours of WorkMay need to work outside of standard working hours at timesThis role is currently working onsite and is expected to work onsite for working hours, with flexibility to work start time.

The work location for this role is in Redmond, WA.Compensation and Benefits:The expected base salary range for this position is $100,000 - $160,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.While most offers typically fall within thelow to mid-pointof the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.SystImmune is a leading and well-funded biotech company with a bright future.

We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.SystImmune