We're seeking a Member of Technical Staff for Translational Medicine to be Latch's expert on human disease and clinical evidence.
Own the translational endpoints in our long-horizon therapeutics and disease benchmarks. Make sure every claim Latch makes stands up to scrutiny from a board-certified geneticist, a regulator, or a treating physician. Build the partnerships that get clinical data in the door and the translational capability to use it in a meaningful way.
Own translational endpoints across our therapeutics and disease benchmarks
Serve as the clinical authority for internal R&D teams across omics, therapeutics, and biosecurity
Build partnerships with patient cohorts, nonprofits, health systems, and biotechs to source clinical data for training and evaluating agents
Negotiate data use agreements and stand up consent, de-identification, and compliance workflows for clinically sensitive data
Translate real drug programs and trial designs into benchmark tasks agents can be scored against
Build a function beyond yourself
MD with residency completed
Has defined clinical endpoints for real drug programs
Was part of at least one clinical trial at any phase as a physician or investigator. You can describe the molecule, patient population, dose rationale, safety profile, and regulatory or safety board feedback
Can identify and reason about disorders of human development caused by genetic mutations
Strong communicator
Translational judgement — You know what an endpoint has to do to survive review
Data rights — You have negotiated data use agreements and understand consent and de-identification cold
Partnerships — You have secured data or research partnerships with patient groups, nonprofits, academics, health systems, or biotechs. You know where clinical data lives and how to get access
Clinical genetics — Depth in Mendelian and developmental disease
Compliance — You can build the function, not just follow it
AI — You are resourceful in leveraging AI tools across clinical and scientific domains
Rare disease or gene therapy experience
Molecular pathology background
Experience building datasets for model training or evaluation
Be able to walk through one molecule end to end. The mechanism, population, dose rationale, endpoint selection, what the regulators said, and what you did.
$250-$400k total comp, based on clinical and technical depth
Variable compensation + equity + stock options
100% premium covered Blue Shield platinum health plan ($0 deductible / $0 out-of-pocket)
Free meals (lunch and dinner)
Waterfront office in China Basin, San Francisco
Full-time, in-person
Location: San Francisco, CA. In-person.
Originally posted by Latch Bio. View original posting
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